Fermentation process for the preparation of L-amino acids...

Details Fermentation process for the preparation of L-amino acids... Fermentation process for the preparation of L-amino acids...

2005-07-12

2005-07-12

Prouty, Rebecca E. (Department: 1652)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing alpha or beta amino acid or substituted amino acid...

C435S115000, C435S116000, C435S015000, C435S320100, C435S252300, C435S252330, C435S194000

Reexamination Certificate

active

06916637

ABSTRACT:
The invention relates to a fermentation process for the preparation of L-amino acids, especially L-threonine, in which the following steps are carried out:a) fermentation of the microorganisms of the family Enterobacteriaceae producing the desired L-amino acid, in which microorganisms at least the pckA gene and/or the open reading frames yjfA and ytfP are, individually or jointly, attenuated and, in particular, switched off,b) enrichment of the L-amino acid in the medium or in the bacterial cells, andc) isolation of the L-amino acid.

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