Fermentation process for the manufacture of an organic compound

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound

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435163, 435165, 435164, 435316, 202180, C12P 706, B01D 342, C12M 102

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043496288

ABSTRACT:
A process for the manufacture of ethanol or a like volatile organic compound by fermenting a carbohydrate with a micro-organism which will convert the carbohydrate into ethanol or a like volatile organic compound, continuously transferring a portion of the fermentation medium to a separator where ethanol or the like volatile organic compound is evaporated from the fermentation medium at a temperature which is not deleterious to the micro-organism by subjecting the fermentation medium to a reduced pressure and recycling part or all of the remaining fermentation medium to the fermenter, the rate of the circulation of fermentation medium from the fermenter to the separator and back being such that the amount of ethanol or like volatile organic compound in the fermentation medium in the fermenter is kept sufficiently low so as not to detrimentally affect the rate of fermentation, compressing the vapor issuing from the separator thereby raising its temperature, and recondensing the compressed vapor in a heat transfer system to provide heat for use in evaporating ethanol or the like volatile organic compound from the fermentation medium in the separator.

REFERENCES:
patent: 419332 (1890-01-01), Horne
patent: 2206024 (1937-08-01), Brown
patent: 2440925 (1944-04-01), Boeckeler
patent: 3972775 (1976-09-01), Wilke et al.
patent: 4009075 (1977-02-01), Hoge
Cysewski et al., Process Design and Economic Studies of Alternative Fermentation Methods for Production of Ethanol, Biotechnology and Bioeng., vol. XX, pp. 1421-1444 (1978).

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