Fermentation process for production of alpha-isopropylmalic acid

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound

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435172, 435255, 435923, C12P 700, C12N 1500, C12N 114, C12R 1645

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active

044079532

ABSTRACT:
A process for producing alpha-isopropylmalic acid by aerobically fermenting a new strain of Yarrowia lipolytica and for recovering said acid from a fermentation medium.

REFERENCES:
patent: 3843466 (1974-10-01), Akabori et al.
patent: 3986933 (1976-10-01), Maldonado et al.
Kirk-Othmer, Encyclopedia of Chemical Technology, 3rd Edition; John Wiley and Sons (1981); pp. 903-907.
Calvo et al., "The Absolute Configuration of .alpha.-Hydroxy-.beta.-Carboxyisocaproic Acid (3-Isopropylmalic Acid), an Intermediate in Levcine Biosynthesis", Biochemistry, 3 (1964), pp. 2024-2027.
Sai, Agr. Biol. Chem. 32, 522-524 (1968).

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