Fermentation process for preparation of antibiotic Bu-2517

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Using tissue cell culture to make a protein or polypeptide

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435253, C12P 2102, C12N 120

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active

045336318

ABSTRACT:
Disclosed is a process for preparation of the water-soluble peptide antibiotic designated Bu-2517 by fermentation of Empedobacter sp. strain G393-B445 (ATCC 31962).

REFERENCES:
patent: 3061516 (1962-10-01), Hooper et al.
patent: 3126317 (1964-03-01), Heineman et al.
Heineman, B. et al., Amphomycin, A New Antibiotic, Dec. 1953, Antibiotics and Chemotherapy.
Bodansky, M. et al., Structure of the Peptide Antibiotic Amphomycin, Apr. 4, 1973, J. Am. Chem. Soc., pp. 2352-2357.
Takahara, Y. et al., Isolation of a New Peptide Antibiotic . . . J. of Antibiotics, Feb. 1979, pp. 115-120.
Takeuchi, Y. et al., The Structure of Permetin A . . . in J. of Antibiotics, Feb. 1979, pp. 121-129.
Kupak, J. et al., Antibiotics from Basidiomycetes . . . J of Antibiotics, Feb. 1979, pp. 130-135.
Misiek, M. et al., Telomycin, A New Antibiotic Antibiotics Annual 1957-1958, pp. 852-855.

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