Fermentation method for producing hyaluronic acid

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

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435885, 536 551, 536 553, C12P 1904, C12R 146, C07H 506, C08B 3700

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048015393

ABSTRACT:
Streptolysin-free hyaluronic acid is produced by cultivating a microorganism belonging to a genus Steptococcus which is anhemolytic and is capable of producing hyaluronic acid (e.g., Streptococcus zooepidemicus FERM BP-784) in a culture medium.

REFERENCES:
patent: 4517295 (1985-05-01), Bracke et al.
Buchanan et al., "Recovery of Microorganisms from Synovial and Pleural Fluids of Animals using Hyperosmolar Media", Veterinary Microbiology , v. 7 (1982); pp. 19-33.
B. Holmstrom, Appl. Microbial, 15 (6), 1409-1413 (1967).
J. B. Woolcock, J. Gem. Microbial, 85, 372-375 (1974).
E. Kjem, Acta Pathol. Microbial. Scand., 84(3), 162-164 (1976).

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