Chemistry: molecular biology and microbiology – Condition responsive control process
Patent
1992-10-23
1995-06-20
Jones, W. Gary
Chemistry: molecular biology and microbiology
Condition responsive control process
435812, 435818, C12Q 300
Patent
active
054260248
ABSTRACT:
A method for aerobic production of microbial cells and/or cell metabolites in a fermentation vessel having at least a riser and at least a downcomer. The method is especially useful to conduct high cell density fermentation processes and involves the controlled addition of an antifoam agent, for maintaining a predetermined and relatively high gas hold up within the fermentor. Also disclosed are various types of fermentors for practicing the method of the invention.
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Flores-Cotera Luis B.
Garcia-Salas Sergio
Centro De Investigacion Y De Estudios Avanzados Del Instituto
Edwards Laura E.
Jones W. Gary
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