Fermentation method and fermentor

Chemistry: molecular biology and microbiology – Condition responsive control process

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435812, 435818, C12Q 300

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active

054260248

ABSTRACT:
A method for aerobic production of microbial cells and/or cell metabolites in a fermentation vessel having at least a riser and at least a downcomer. The method is especially useful to conduct high cell density fermentation processes and involves the controlled addition of an antifoam agent, for maintaining a predetermined and relatively high gas hold up within the fermentor. Also disclosed are various types of fermentors for practicing the method of the invention.

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