Fermentation broth degassification

Details Fermentation broth degassification Fermentation broth degassification

1990-05-29

1992-09-22

Warden, Robert J.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Foam culture

435255, 435256, 435812, 435813, 435819, 55 41, 55 52, 261DIG19, C12N 134, C12M 121

Patent

active

051496526

ABSTRACT:
A post-fermentation degassing technique is provided for use in degassing foamed fermentation broths containing cultured microorganisms. Such a broth is charged while pressurized through a nozzle to form a spray suspension in a gaseous spray chamber located in a gravitationally upper part of a degassing vessel. The spray chamber is vented to the atmosphere. The spray suspension is coalesced to form a bulk liquid phase located in a gravitationally lower portion of the degassing vessel whereby the upper surface of such bulk liquid phase forms the bottom surface of such spray chamber. The nozzle is so oriented that the spray suspension it produces is downwardly directed towards the surface of the bulk liquid phase and the layer of foam characteristically foamed thereon. Additionally, a portion of the bulk liquid phase is recycled to the upper part of the vessel through a second nozzle to form a second spray suspension which is coalesced into the bulk liquid phase.

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