Fenofibrate-containing composition

Details Fenofibrate-containing composition Fenofibrate-containing composition

2007-03-13

2007-03-13

Hartley, Michael G. (Department: 1618)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

C424S456000, C514S962000

Reexamination Certificate

active

10469305

ABSTRACT:
A novel fenofibrate-containing composition having equivalent bioavailability, when compared to conventional capsules, is effective in reducing the size of the conventional capsule preparations. The fenofibrate-containing composition comprises the following formula:(a) fenofibrate100parts by weight,(b) a solid surfactant3 to 4parts by weight,(c) lactose1 to 2parts by weight, and(d) magnesium stearate1 to 2parts by weight,in admixture with a binder and a disintegrator, wherein the sum of said binder and said disintegrator is 17 to 20 parts by weight, and the fenofibrate and the solid surfactant are co-micronizates.

REFERENCES:
patent: 4895726 (1990-01-01), Curtet et al.
patent: 5827536 (1998-10-01), Laruelle
patent: 6074670 (2000-06-01), Stamm et al.
patent: 0 904 781 (1999-03-01), None
patent: 5-194209 (1993-08-01), None

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