Feline T-lymphotropic lentivirus assay

Details Feline T-lymphotropic lentivirus assay Feline T-lymphotropic lentivirus assay

1990-11-16

1992-06-02

Kepplinger, Esther L.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving virus or bacteriophage

435 792, 436518, C12Q 170

Patent

active

051186020

ABSTRACT:
Compositions derived from a novel viral isolate designated feline T-lymphotropic lentivirus (FTLV) include the whole virus; proteins, polypeptides and, polynucleotide sequences derived from the virus; and antibodies to antigenic sites on the virus. These compositions are useful in a variety of techniques for the detection of and vaccination against FTLV. Detection methods disclosed include immunoassays for both the virus and antibodies to the virus, and the use of polynucleotide probes to detect the viral genome. Vaccines include both wholly and partially inactivated viruses and subunit vaccines. Whole, live virus is also useful as a model system for predicting the behavior of human immunodeficiency virus (HIV).

REFERENCES:
Pedersen et al., Science 235:791-793, 1987.
American Assoc. for Can. Res., May 23, 1987, Ab. No. 3337.
The 3rd Int'l. Conf. on AIDS, Jun. 1-5, 1987.
Fed. Amer. Soc. for Experimental Biology, Apr. 2, 1987.

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