Feline t-lymphotropic lentivirus

Details Feline t-lymphotropic lentivirus Feline t-lymphotropic lentivirus

1990-11-16

1991-08-06

Schwartz, Richard A.

Chemistry: molecular biology and microbiology

Virus or bacteriophage, except for viral vector or...

435 5, 435948, 424 89, 530387, C12N 700, C12Q 170, A61K 3921, C07K 1500

Patent

active

050377531

ABSTRACT:
Compositions derived from a novel viral isolate designated feline T-lymphototropic lentivirus (FTLV) include the whole virus; proteins, polypeptides and, polynucleotide sequences derived from the virus; and antibodies to antigenic sites on the virus. These compositions are useful in a variety of techniques for the detection of and vaccination against FTLV. Detection methods disclosed include immunoassays for both the virus and antibodies to the virus, and the use of polynucleotide probes to detect the viral genome. Vaccines include both wholly and partially inactivated viruses and subunit vaccines. Whole, live virus is also useful as a model system for predicting the behavior of human immunodeficiency virus (HIV).

REFERENCES:
Davis, Bernard David; Microbiology, 3rd Edition, p. 942, Harper & Row, New York, 1980.
Pedersen et al. (1987) Science 235:790-793.
Abstract No. 3337- Am. Assoc. for Can. Res. 5/23/87.
Third International Conf. on AIDS, Jun. 1-5, 1987.
Federation of American Society for Experimental Biology, Apr. 2, 1987.

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