Feline leukemia virus vaccine plasmids for fusion protein of the

Chemistry: molecular biology and microbiology – Vector – per se

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435 68, 4351723, 435253, 935 27, 935 29, 935 38, 935 47, 935 73, 530808, 530820, 530826, C12N 100, C12N 1500

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047014164

ABSTRACT:
Polypeptides that are synthesized or expressed directly in microorganisms, include an amino acid sequence that is homologous to at least a portion of gp70 envelope protein of FELV, and are immunogens that elicit or prime a humoral response in cats and immunize cats against FeLV infection. The microbially produced polypeptides are exemplified by a group of E. coli-expressed fusion proteins that comprise a portion of the trp leader peptide and a portion of the trp E protein fused to various portions of a subgroup B gp70 envelope protein. The synthesized polypeptides are exemplified by polypeptides that are homologous to segments of the hydrophilic domains of the gp70 protein.

REFERENCES:
patent: 4406885 (1983-09-01), Pinter
patent: 4434157 (1984-02-01), Olsen
Science (1981) 214, pp. 1125-1148, Kleid et al.
Science (1981) 219, pp. 614-620, Yelverton et al.
Nature (1981) 304, pp. 699-703, Emini et al.
J. Virology (1982) 44, pp. 19-31, Basselman et al.
J. Virology (1983) 46(3), pp. 829-840, Sal et al.
J. Virology (1983) 46(3), pp. 871-880, Elder et al.
Gene (1979) 7, pp. 79-82, Rad et al.
J. Nunberg et al., Nucleotide Sequences of the Envelope Genes of Two Isolates of Feline Leukemia Virus Subgroup B, J. Virology 49, 629-632 (1984).
J. Elder and J. Mullins, Neucleotide Sequence of the Envelope Gene of Gardner-Arnstein Feline Leukemia Virus B Reveals Unique Sequence Homologies with a Murine Mink Cell Focus-Forming Virus, J. Virology 46, 871-880 (1983).
M. Lewis et al., Protection Against Feline Leukemia by Vaccination with a Subunit Vaccine, Infect. Immun. 34, 888-893 (1981).
R. Salerno et al., Feline Leukemia Virus Envelope Glycoprotein in Vaccine: Preparation and Evaluation of Immunizing Potency in Guinea Pig and Cat, J. Natl. Cancer Inst. 61, 1487-1493 (1978).

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