Drug – bio-affecting and body treating compositions – Lymphokine
Patent
1987-08-14
1989-10-24
Nucker, Christine M.
Drug, bio-affecting and body treating compositions
Lymphokine
530350, 530403, 530806, 935 65, A61K 3702
Patent
active
048760897
ABSTRACT:
Methods and compositions are provided for the efficient production of a polypeptide having immunological reactivity corresponding to that of naturally-occurring envelope glycoproteins of feline leukemia virus. A DNA construct including a replication system recognized by yeast, and a viral envelope protein gene under the transcriptional control of a yeast promoter, and terminator is provided. By transforming a yeast host with the DNA construct, enhanced yields of the product may be obtained.
Saccharomyces carlsbergensis strains 2150-2-3 (pCP-envB-R) and 2150-2-3 (pCP-envA-R) were deposited at the American Type Culture Collection on July 18, 1984, and granted accession nos. 20720 and 20721, respectively.
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Luciw Paul
Parkes Deborah L.
Van Nest Gary A.
Chiron Corporation
Nucker Christine M.
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