Feline interferon and process for production thereof

Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses

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4353201, 935 32, C12N 1520, C12N 1586

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active

051943816

ABSTRACT:
A recombinant silkworm nuclear polyhedrosis virus containing DNA coding for a protein of feline interferon; the recombinant virus is constructed by cotransfection a recombinant plasmid having a gene coding for a protein of feline interferon and a silkworm nuclear polyhedrosis virus DNA into established silkworm cells, and cloning the desired recombinant virus. The recombinant virus is useful for a mass-production of feline interferon.

REFERENCES:
Yamamoto et al., Vet. Immunol. Immunopath., vol. 11, 1986, pp. 1-19.
Kozak, Cell. vol. 44, 1986, pp. 283-292.
Horiuchi et al., Agricultural and Biological Chemistry, vol. 51, No. 6, pp. 1573-1580 (1987).
Maeda et al., Nature, vol. 315, No. 6020, pp. 592-594 (1985).

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