Feline interferon and process for production thereof

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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4353201, C12P 2102, C12N 1500

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active

054809568

ABSTRACT:
A recombinant silkworm nuclear polyhedrosis virus containing DNA coding for a protein of feline interferon; the recombinant virus is constructed by cotransfection a recombinant plasmid having a gene coding for a protein of feline interferon and a silkworm nuclear polyhedrosis virus DNA into established silkworm cells, and cloning the desired recombinant virus. The recombinant virus is useful for a mass-production of feline interferon.

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Horiuchi, et al., High Level Expression of the Human-a-Interferon Gene through the Use of an Improved Baculovirus Vector in the Silkwork, Bombyx Mori, Agricultural and Biological Chemistry, vol. 51, No. 6, pp. 1573-1580, 1987.
Maeda, et al., Production of Human Interferon in Silkworm Using a Baculovirus Vector, Nature, vol. 315, No. 6020, pp. 592-594, 1985.

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