Feline immunoglobulin E proteins and compositions thereof

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

Reexamination Certificate

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C530S388220, C424S133100, C424S141100, C424S144100, C424S185100, C536S023530

Reexamination Certificate

active

10409772

ABSTRACT:
The invention relates to: nucleic acid molecules encoding the light chain and heavy chain of feline immunoglobulin E (IgE), including species-specific regions of feline IgE; proteins encoded by the nucleic acid molecules; inhibitors to the nucleic acids and proteins; antibodies to the proteins; cells transformed with the nucleic acid molecules; assays employing the transformed cells, nucleic acids, antibodies and/or proteins or portions thereof; methods for treating IgE-mediated responses (ie. allergy) using the materials provided; methods for eliciting an immune response to IgE and kits containing the nucleic acid molecules, proteins or derivatives thereof (ie. antibodies).

REFERENCES:
patent: 5965709 (1999-10-01), Presta et al.
Colman PM, Research in Immunology, 1994, 145:33-36.
Gilbert et al., Veterinary Immunology and Immunopathology, 1998, 63:223-233.

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