Feline immunodeficiency virus isolate NCSU.sub.1

Details Feline immunodeficiency virus isolate NCSU.sub.1 Feline immunodeficiency virus isolate NCSU.sub.1

1994-12-29

1997-09-09

Fleisher, Mindy

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

4352523, 43525233, 4352542, 4353201, 435948, 435348, 435350, 435362, 435367, 435364, 435365, 536 2372, C12N 500, C12N 700, C12N 702, C12N 1549

Patent

active

056655924

ABSTRACT:
Disclosed is an isolated and purified feline immunodeficiency virus (FIV) culture having the identifying characteristics of FIV isolate NCSU.sub.1. A biologically pure culture of host cells containing a FIV having the identifying characteristics of FIV isolate NCSU.sub.1 is also disclosed, along with isolated and purified DNA coding for (a) an FIV having the identifying characteristics of FIV isolate NCSU.sub.1, or (b) an antigenic fragment of an FIV having the identifying characteristics of FIV isolate NCSU.sub.1. Various vaccine formulations containing active agents derived from the foregoing FIV virus, DNA encoding the virus, and DNA encoding antigenic fragments of the virus are also disclosed herein.
Also disclosed are immunodeficient mice containing feline tissue, which feline tissue is capable of infection with a feline immunodeficiency virus such as (but not limited to) FIV isolate NCSU.sub.1.

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