Feline Fc epsilon receptor alpha chain proteins and therapeutic

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

530350, C07K 14435, C07K 14705, A61K 3817, A61K 3935

Patent

active

059588802

ABSTRACT:
The present invention relates to feline Fc epsilon receptor alpha chain nucleic acid molecules, proteins encoded by such nucleic acid molecules, antibodies raised against such proteins, and inhibitors of such proteins. The present invention also includes methods to detect IgE using such proteins and antibodies. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies and/or inhibitory compounds as well as the use of such therapeutic compositions to mediate Fc epsilon receptor-mediated biological responses.

REFERENCES:
patent: 4962035 (1990-10-01), Leder et al.
Alberts et al. Molecular Biology of the Cell, New York:Garland Publishing, Inc. pp. 264-266, 1983.
Ravetch et al. Ann. Rev. Immunol. 9, 457-92, 1991.
Mohr et al. Am. J. Vet. Res. 53, 820-828, 1992.
Ra et al. J. Biol. Chem. 264, 15323-15327, 1989.
Hayashi, et al., Genbank Accession No. D16413, submitted Jun. 8, 1993.
Kochan, et al., "Isolation of the Gene Coding for the Alpha Subunit of the Human High Affinity IgE Receptor," (1988) Nucleic Acids Res. 16(8 ), p. 3584.
Kuster, et al., "Characterization and Expression of the Gene for the Human Fc Receptor .gamma.Subunit," (1990) J. Biol. Chem. 265(11 ), pp. 6448-6452.
Kuster, et al., "The Gene and cDNA for the Human High Affinity Immunoglobulin E Receptor .beta.Chain and Expression of the Complete Human Receptor," (1992) J. Biol. Chem. 267(18), pp. 12782-12787.
Lowenthal, et al., "Passive Transfer of IgE-Mediated Cutaneous Reactivity in Heterologous Species," (1993) Annals of Allergy 71, pp. 481-484.
Pang, et al., "Characterization of the Gene for the Human High Affinity IgE Receptor (Fc.epsilon.RI) .alpha.-Chain," (1993) J. Immunol. 151(11), pp. 6166-6174.
Shimizu, et al., "Human and Rat Mast Cell High-Affinity Immunoglobulin E Receptors: Characterization of Putative .alpha.-Chain Gene Products," (1988), Proc. Natl. Acad. Sci. USA (85), pp. 1907-1911.
George et al. in Macromolecular Sequencing and Synthesis, pp. 127-149, 1988 .

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Feline Fc epsilon receptor alpha chain proteins and therapeutic does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Feline Fc epsilon receptor alpha chain proteins and therapeutic , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Feline Fc epsilon receptor alpha chain proteins and therapeutic will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-703210

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.