Feline Fc epsilon receptor alpha chain nucleic acid molecules, a

Details Feline Fc epsilon receptor alpha chain nucleic acid molecules, a Feline Fc epsilon receptor alpha chain nucleic acid molecules, a

1998-01-09

2000-08-15

Mertz, Prema

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 711, 435 712, 435325, 43525411, 435471, 4353201, 4352523, 536 235, 536 243, 536 2431, 530350, C12N 1512, C12N 1563, C07K 14705

Patent

active

061034940

ABSTRACT:
The present invention relates to feline Fc epsilon receptor alpha chain nucleic acid molecules, proteins encoded by such nucleic acid molecules, antibodies raised against such proteins, and inhibitors of such proteins. The present invention also includes methods to detect IgE using such proteins and antibodies. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies and/or inhibitory compounds as well as the use of such therapeutic compositions to mediate Fc epsilon receptor-mediated biological responses.

REFERENCES:
patent: 4962035 (1990-10-01), Leder et al.
Reiger et al. (Glossary of Genetics and Cytogenetics, 4.sup.th ed, Springer Valey Berlin) 1976.
Hayashi, et al., Genbank Accession No. D16413, submitted Jun. 8, 1993.
Kochan, et al., "Isolation of the Gene Coding for the Alpha Subunit of the Human High Affinity IgE Receptor," (1988) Nucleic Acids Res. 16(8),p. 3584.
Kuster, et al., "Characterization and Expression of the Gene for the Human Fc Receptor .gamma. Subunit," (1990) J. Biol. Chem. 265(11),pp. 6448-6452.
Kuster, et al., "The Gene and cDNA for the Human High Affinity Immunoglobulin E Receptor .beta. Chain and Expression of the Complete Human Receptor," (1992) J. Biol. Chem. 267(18), pp. 12782-12787.
Lowenthal, et al., "Passive Transfer of IgE-Mediated Cutaneous Reactivity in Heterologous Species," (1993) Annals of Allergy 71, pp. 481-484.
Pang, et al., "Characterization of the Gene for the Human High Affinity IgE Receptor (Fc.epsilon.RI) .alpha.-Chain," (1993) J. Immunol. 151(11), pp. 6166-6174.
Shimizu, et al., "Human and Rat Mast Cell High-Affinity Immunoglobulin E Receptors: Characterization of Putative .alpha.-Chain Gene Products," (1988), Proc. Natl. Acad. Sci. USA (85), pp. 1907-1911.
George, et al., "Current Methods in Sequence Comparison and Analysis," (1988)Macromolecular Sequencing and Synthesis Selected Methods and Applications pp. 127-149.

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