Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Feline cell – per se
Patent
1997-04-29
1998-12-08
Smith, Lynette F.
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Feline cell, per se
435325, 435326, 435 5, C12N 300, C12Q 170
Patent
active
058468250
ABSTRACT:
The subject invention pertains to novel methods and compositions for protecting cats from infection by a broad range of FIV strains using a multi-subtype FIV vaccine. Multi-subtype FIV vaccines comprising either cell free whole virus or cell lines infected with viruses are described. Methods for vaccinating cats with the subject vaccine compositions are also described. Cats vaccinated according to the methods and compositions of the subject invention exhibit protective humoral and cellular immune responses to FIV when challenged with homologous or heterologous strains of FIV. The subject invention also pertains to novel feline cell lines that are susceptible to infection by FIV and their methods of use.
REFERENCES:
patent: 5275813 (1994-01-01), Yamamoto et al.
Pedersen, N.C., E.W., Ho, M.L. Brown, J.K. Yamamoto (1987) "Isolation of a T-lymphotropic virus from domestic cats with an immunodeficiency-like syndrome," Science 235:790-793.
Yamamoto, J.K., N.C. Pedersen, E.W. Ho, T. Okuda, G.H. Theilen (1988a) "Feline immunodeficiency syndrome--a comparison between feline T-lymphotropic lentivirus and feline leukemia virus," Leukemia, Dec. Supplement 2:204S-215S.
Yamamoto, J.K., E. Sparger, E.W. Ho, P.H. Andersen, T.P. O'Connor, C.P. Mandell, L. Lowenstine, N.C. Pedersen (1988) "Pathogenesis of experimentally induced feline immunodeficiency virus infection in cats," Am. J. Vet. Res. 49:1246-1258.
Ackley, C.D., J.K. Yamamoto, N.B. Levy, N.C. Pederson, M.D. Cooper (1990) "Immunologic abnormalities in pathogen-free cats experimentally infected with feline immunodeficiency virus," J. Virol. 64:5652-5655.
Olmsted, R.A., A.K. Barnes, J.K. Yamamoto, V.M. Hirsch, R.H. Purcell, P.R. Johnson (1989) "Molecular cloning of feline immunodeficiency virus," Proc. Nat. Acad. Sci. 86:2448-2452.
Olmsted, R.A., V.M. Hirsch, R.H. Purcell, P.R. Johnson (1989) "Nucleotide sequence analysis of feline immunodeficiency virus: Genome organization and relationship to other lentivirus," Proc. Natl. Acad. Sci. USA 86:8088-8092.
Talbott, R.L., E.E. Sparger, K.M. Lovelace, W.M. Fitch, N.C. Pedersen, P.A. Luciw, J.H. Elder (1989) "Nucleotide sequence and genomic organization of feline immunodeficiency virus," Proc. Natl. Acad. Sci. USA 86:5743-5747.
Hosie, M.J., O. Jarrett (1990) "Serological responses of cats to feline immunodeficiency virus," AIDS 4:215-220.
Murphy, F., D.W. Kingsbury (1990) "Virus Taxonomy," In Fields Virology, 2nd Ed., B.N. Fields, D.M. Knipe et al., eds, Raven Press, New York, Chapter 2, pp. 9-36.
Sodora, D.L., E.G. Shpaer, B.E. Kitchell, S.W. Dow, E.A. Hoover, J.I. Mullins (1994) "Identification of three feline immunodeficiency virus (FIV) env gene subtype and comparison of the FIV and human immunodeficiency virus type 1 evolutionary patterns," J. Virol. 68:2230-2238.
Rigby, M.A., E.C. Holmes, M. Pistello, A. Mackay, A.J. Leight-Brown, J.C. Nell (1993) "Evolution of structural proteins of feline immunodeficiency virus: molecular epidemiology and evidence of selection for change," J. Gen. Virol. 74:425-436.
Kakinuma, S., K. Motokawa, T. Hohdatsu, J.K. Yamamoto, H. Koyama, H. Hashimoto (1995) "Nucleotide Sequence of Feline Immunodeficiency Virus: Classification of Japanese Isolates in Two Subtypes Which Are Distinct from Non-Japanese Subtypes," Journal of Virology 69(6):3639-3646.
Nelson Brett
Smith Lynette F.
University of California
University of Florida
LandOfFree
Feline derived T-cell lines for producing FIV does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Feline derived T-cell lines for producing FIV, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Feline derived T-cell lines for producing FIV will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-176614