Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...
Reexamination Certificate
2007-03-27
2007-03-27
Prouty, Rebecca E. (Department: 1652)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing alpha or beta amino acid or substituted amino acid...
C435S069100, C435S106000, C435S252300, C435S252800, C435S320100, C435S471000, C536S023200
Reexamination Certificate
active
10530844
ABSTRACT:
The invention relates to a homoserine transsuccinylase, which exhibits reduced sensitivity towards L-methionine or SAM in comparison with a homoserine transsuccinylase wild-type enzyme, whereby the latter comprises an amino acid sequence containing a TyrGlnXaaThrPro sub-sequence, the Thr of said sub-sequence lying between positions285and310of the amino acid sequence and position1being filled by the starter methionine. The inventive homoserine transsuccinylase is characterized in that in comparison with the wild-type enzyme at least 2 amino acids are modified, said modification taking place in the Thr of the sub-sequence or in the C-terminal.
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Thomson Derwent abstract corresponding to JP2000-139471A.
Derwent abstract corresponding to DE 102 47 437 A1.
Bauer Brigitte
Leonhartsberger Susanne
Pfeiffer Kerstin
Winterhalter Christoph
Collard & Roe P.C.
Consortium für elektrochemische Industrie GmbH
Prouty Rebecca E.
Raghu Ganapathirama
LandOfFree
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