Feed additive for ruminants

Details Feed additive for ruminants Feed additive for ruminants

1997-02-04

1998-07-07

Levy, Neil S.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Specially adapted for ruminant animal

426807, A23K 100

Patent

active

057764832

DESCRIPTION:

BRIEF SUMMARY
This application is a 371 of PCT/JP96/01627 filed Jun. 14,1996.
1. Field of the Invention
The present invention relates to a feed additive and, more particularly to a matrix-type rumen bypass formulation of feed additives wherein a biologically-active substance nutritiously useful for ruminants is dispersed in a protective material for protecting said biologically-active substance.
2. Background Art
A rumen bypass formulation for ruminants is defined as a formulation of feed additives which comprises one or more of amino acids, vitamins and other biologically-active substance and has a specific characteristic to allow elution and absorption of said biologically-active substance in digestive organs of ruminants from their fourth stomach onward while restricting elution and microbial decomposition of said substance in their rumen.
In breeding of ruminants, it is well accepted from dietetic and clinical point of view to feed them together with biologically-active substance contained in a rumen bypass formulation. In the practices, the incorporation of a biologically-active substance at high concentration to a rumen bypass formulation is advantageous and favorable, economically. Where, the hardness of the formulation is very important in view of durability to a mixing process with feeds and to chewing of cows. However, when increasing the concentration of biologically-active substance in the formulation, it is required to reduce the content of a protective material in the formulation, which has therefore made difficult to maintain rumen bypass property and hardness of the formulation. In order to solve this problem, a protective material having higher performance than the previous be inevitably required. Under the absence of such protective material, the concentration of a biologically-active substance in a matrix-type rumen bypass formulation has been obliged to be less than 50%.
The concept and many practical examples of the rumen bypass formulation has been already publicly known, however, there is no example for a matrix-type formulation which can contain a biologically-active substance at a high concentration of more than 50% (high concentrate formulation in the market). An example which uses salts of aliphatic monocarboxylic acids (fatty acids) as a protective material has been disclosed, however, no example which contains a biologically-active substance at a high concentration of more than 50% and can give good rumen bypass property, has not been disclosed.
In Japanese Patent Laid-opened No. Hei 2-163043, a concept for a matrix-type formulation which uses fatty acid salts and a fatty compound compatible to the salt as a protective material is disclosed, however, the concentration of a biologically-active substance contained therein is lower than 10%, and wherein no concrete description on the formulation containing more than 50% of the biologically-active substance, is given.
On the other hand, a example wherein both fatty acid calcium and stearyl alcohol were used as a protective material at a combining rate of 58:2 (97:3) is disclosed in International Patent Open No. WO/12731, however, the concentration of the biologically-active substance is yet lower than 50%.
In Japanese Patent Laid-opened No. Sho 56-154956, a matrix-type formulation which uses fatty protective material is disclosed, however, the content of the biologically-active substance is lower than 50% and the composition of the protective material is different from the one given in the present invention.
In U.S. Pat. No. 5,425,963, high purity fatty acid salt as a feed additive and the manufacturing method are disclosed, however, the object of that invention is different from that of the present invention and the content of the biologically-active substance is also far different from the one of the present invention.
Considering such difficulty existing in the prior arts, the present invention has an object to provide an economically advantageous rumen bypass formulation which can contain a biologically-active substance at a high concentrati

REFERENCES:
patent: 3959493 (1976-05-01), Baalsrud et al.
patent: 4642317 (1987-02-01), Palmquist et al.
patent: 4798737 (1989-01-01), Brunton et al.
patent: 4826694 (1989-05-01), McAskie
Sasaoka, S., "Feed Additive for Ruminant", Japanese Abstract No. 2-163043(A), Jun. 22, 1990.
Sasaoka, S., "Feed Additive for Ruminant", Japanese Abstract No. 2-163044(A), Jun. 22, 1990.

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