Fecal occult blood test reagent

Details Fecal occult blood test reagent Fecal occult blood test reagent

1988-03-31

1989-04-04

Marcus, Michael S.

Chemistry: analytical and immunological testing

Hemoglobin, myoglobin, or occult blood

435 28, 436904, G01N 2178, G01N 3372

Patent

active

048187020

ABSTRACT:
Fecal occult blood tests of enhanced sensitivity, specificity, and readability are provided by employing (1) a developer or complete reagent solution that uses as a solvent system a solvent comprising at least about 50% by volume of a solvent for iron protoporphyrins such as dimethyl sulfoxide and/or (2) a multi-chromogen comprised of a mixture of guaiac and ABTS. Test results may be further improved by incorporating hemoprotein solubilizing agents, plant peroxidase inhibitors, iron/copper chelating agents, accelerators and buffers in the developer/reagent.

REFERENCES:
patent: 3252762 (1966-05-01), Adams, Jr. et al.
patent: 3278394 (1966-10-01), Harvill et al.
patent: 3406015 (1968-10-01), Foster
patent: 3413197 (1968-11-01), Fraser
patent: 3627698 (1971-12-01), Rey et al.
patent: 3642444 (1972-02-01), Guehler et al.
patent: 3653836 (1972-04-01), Gruber et al.
patent: 3721607 (1973-03-01), Gruber et al.
patent: 3917452 (1975-11-01), Rittersdorf et al.
patent: 3996006 (1976-12-01), Pagano
patent: 4017261 (1977-04-01), Svoboda et al.
patent: 4035150 (1977-07-01), Jaffe
patent: 4071317 (1978-01-01), Lam
patent: 4089747 (1978-05-01), Bruschi
patent: 4211845 (1980-07-01), Genshaw et al.
patent: 4219336 (1980-08-01), Guthlein et al.
patent: 4220713 (1980-09-01), Rittersdorf et al.
patent: 4251222 (1981-02-01), White
patent: 4251223 (1981-02-01), White
patent: 4260393 (1981-04-01), Gibson
patent: 4278439 (1981-07-01), White
patent: 4318984 (1982-03-01), Magers et al.
patent: 4333734 (1982-06-01), Fleisher
patent: 4378971 (1983-04-01), Schwartz
patent: 4493892 (1985-01-01), Fleisher
patent: 4578358 (1986-03-01), Oksman et al.
patent: 4676950 (1987-06-01), Foster
Chem. Abstracts, vol. 102, 1985, 102:2733q.
Chem. Abstracts, vol. 103, 1985, 103:50884g.
Chem. Abstracts, vol. 101, 1984, 101:126200n.
Chem. Abstracts, vol. 74, 1971, 74:51331u.
Gallagher, W. A., et al., Biochem. J. (1968) 108:131.
Brown, S. B., et al., Biochem. J. (1970) 117:741-744.
Jones, P., et al., Biochem. J. (1973) 135:353-359.
Jones, P., et al., Biochemistry (1974) vol. 13, No. 21, 4279-4284.
Scheller, J. F., et al., Acta. Biol. Med. Ger. (1975) 34:319-324.
Brown, S. B., et al., Biochem. J. (1976) 153:279-285.
Nishide, H., et al., Biochimica et Biophysica Acta (1977) 498:208-214.
Adams, P. A., Biochem. J. (1979) 179:273-280.
Collier, G. S., et al., Biochem. J. (1979) 179:281-289.
Ahlquist, D. A., et al., (1984) Annals of Internal Medicine, vol. 101, No. 3, 297-302.
New England J. of Med., (1985) 1448-1450.
Ahlquist, D. A., et al., (1985) New England J. of Med., vol. 312, No. 22, 1422-1428.

Affiliated with

Also associated with

Rating

Fecal occult blood test reagent does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Fecal occult blood test reagent, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Fecal occult blood test reagent will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-180245