Chemistry: analytical and immunological testing – Hemoglobin – myoglobin – or occult blood
Patent
1984-12-11
1986-10-07
Turk, Arnold
Chemistry: analytical and immunological testing
Hemoglobin, myoglobin, or occult blood
422 56, 436904, G01N 2178, G01N 3372
Patent
active
046159827
ABSTRACT:
Fecal occult blood tests of enhanced sensitivity and specificity are provided by employing (1) a developer composition comprising a solution of a hydroperoxide in a solvent comprising at least about 50% by volume of a solvent for iron protoporphyrins such as dimethyl sulfoxide and/or (2) a solid test matrix comprising a solid support impregnated with a leuco dye and a hemoprotein solubilizing agent. Test results may be further improved by incorporating plant peroxidase inhibitors, iron/copper chelating agents and buffers in the developer and/or test matrix.
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