FC receptor polymorphism

Details FC receptor polymorphism FC receptor polymorphism

1997-06-03

1999-11-16

Jones, W. Gary

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

536 231, 536 243, C12Q 168, C07H 2102, C07H 2104

Patent

active

059855614

ABSTRACT:
The present invention provides a method for identifying Fc.gamma.RIIIA allelic pattern in a human patient. The present invention also provides methods for determining in a human patient a predisposition to autoimmune diseases and the relative capacity of a human subject to produce anti-tumor antibodies, antibodies directed against viral or bacterial pathogen, or to mount an effective immune response to a vaccine.

REFERENCES:
patent: 5220004 (1993-06-01), Saiki et al.
D. Brian Dawson, Clinical Biochemistry, 23:279-285, 1990.
M. de Haas et al., The Journal of Immunology, 156:2948-2955, 1996.
J. Ravetech et al., Journal of Experimental Medicine, 170:481-497, 1989.
Vance et al., J. of Immunology 151(11): 6429-6439 (1993).
Radeke et al., J.of Immunology 153: 1281-1292 (1994).

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