FC receptor for immunoglobulin

Details FC receptor for immunoglobulin FC receptor for immunoglobulin

1994-10-31

1999-11-16

Ulm, John

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4352523, 4353201, 530350, 536 235, C07K 14705, C12N 1512

Patent

active

059855991

ABSTRACT:
Nucleotide sequences encoding a protein with Fc receptor activity or a fragment thereof that is capable of binding the Fc region of immunoglobulin and polypeptides with Fc receptor activity are provided. Proteins which exhibit enhanced or reduced immunoglobulin binding ability relative to native Fc receptors and nucleotides encoding these proteins also are provided. The invention also provides methods of determining the presence of immunoglobulin, detecting an immune complex, removing immunoglobulin from a body fluid and treating disease using the proteins.

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