Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Oxidoreductase
Patent
1993-11-08
1995-05-02
Fox, David T.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Oxidoreductase
435189, 530377, C12N 902, C12N 904, C07K 300
Patent
active
054118794
ABSTRACT:
By this invention, a solubilized seed-plant fatty acyl reductase protein is provided, wherein said protein is active in the formation of a fatty alcohol from a fatty acyl substrate. Of special interest is a jojoba embryo reductase protein having a molecular mass of about 32 kD or about 47 kD and sequences obtainable therefrom. Also considered are amino acid and nucleic acid sequences obtainable from such fatty acyl reductases.
REFERENCES:
L. Hjelmeland et al. Meth. in Enzymology, vol. 104 (1984) pp. 305-319.
A. Khan et al. Arch. of Biochem. & Biophys., vol. 170, (1975) pp. 400-408.
M. Pollard et al. Lipids, vol. 14, #7 (1979) pp. 651-662.
Hjelmeland et al. Methods in Enzymology, vol. 104 (1984) pp. 305-318.
Kolattukudy, P. E., et al., Methods in Enzymology, vol. 71 (1981) pp. 269-272.
Ohlrogge, J. B., et al. Lipids, vol. 13 (1978) pp. 203-210.
Khan, A. A., et al. Archives of Biochem. and Biophysics, vol. 170 (1975) pp. 400-408.
Pollard et al. "Studies on Biosynthesis of Waxes by Developing Jojoba Seed. II. The Demonstration of Wax Biosynthesis by Cell-Free Homogenates," Lipids (1979) 14:651-662.
Wu, et al., "Studies of Biosynthesis of Waxes by Developing Jojoba Seed: III. Biosynthesis of Wax Esters from Acyl-CoA and Long Chain Alcohols," Lipids (1981) 16:897-702.
Karplus, et al., "Atomic Structure of Ferredoxin-NADP.sup.+ Reductase: Prototype for a Structurally Novel Flavoenzyme Family," Science (1991) 251:60-66.
Wildner and Hallick, "Wax Ester Biosynthesis in Euglena gracilis," abstract from The Southwest Consortium on Plant Genetics and Water Resources Fifth Annual Meeting, Apr. 22-24, 1990, Las Cruces, N.M.
Pushnik, et al., "Characterization of the Biosynthetic Pathway For Formation of Liquid Wax in Jojoba," abstract from The Southwest Consortium on Plant Genetics and Water Resources Fourth Annual Meeting, Feb. 7, 1989, Riverside, Calif.
Kolattukudy, P. E., "Cutin, Suberin, and Waxes", The Biochemistry of Plants, vol. 4 (1980) pp. 571-644.
Yermanos, D. M., "Composition of Jojoba Seed During Development", The Journal of the American Oil Chemistry Society, vol. 52 (1975) pp. 115-117.
Stumpf, P. L., "The Synthesis of Fatty Acids in Plant Systems", Membranes and Transport, vol. 2 (1982) pp. 663-666.
Riendeau, et al., "Enzymatic Reduction of Fatty Acids and Acyl-CoAs to Long Chain Aldehydes and Alcohols", Experientia, vol. 41 (1985) pp. 707-713.
Pollard, et al., "Studies on Biosynthesis of Waxes by Developing Jojoba Seed II. The Demonstration of Wax Biosynthesis By Cell-Free Homogenates", Lipids, vol. 14 No. 7 (1979) pp. 651-660.
Khan, et al., "A Microsomal Fatty Acid Synthetase Coupled to Acyl-CoA Reductase in Euglena gracilis", Archives of Biochemistry and Physics, vol. 158 (1973) pp. 411-420.
Kolattukudy, et al., "Enzymatic Reduction of Fatty Acids and Alpha-Hydroxy Acids", Methods in Enzymology, Lipids vol. 71: part C (1981) pp. 263-275.
Rodriguez, et al., "Purification of the Acyl Coenzyme A reductase Component from a Complex Responsible for the Reduction of Fatty Acids in Bioluminescent Bacteria", The Journal of Biological Chemistry, vol. 258, No. 8 (1983) pp. 5233-5237.
Wall, et al., "Subunit Structure of the Fatty Acid Reductase Complex from Phobacterium Phosphoreum", Biochemistry, vol. 25 (1986) pp. 4315-4321.
Boylan et al., "Lux C, D and E genes of the Vibrio fischeri Luminescence Operon Code for the Reductase, Transferase and Synthetase Enzymes Involved in Aldehyde Biosynthesis," Photochemistry and Photobiology, vol. 49, No. 5 (1989) pp. 681-688.
Lloyd, Geoffrey M., "Synthesis and Translocation of Lipids in the Cell Envelope Membranes of Micrococcus cryophilus," Microbios, vol. 52 (1987) pp. 29-37.
Bordier, C., "Phase Separation of Integral Membrane Proteins in Triton X-114 Solution." The Journal of Biological Chemistry, vol. 256 No. 4 (1981) pp. 1604-1607.
Morre, et al., "Biological Membranes, A practical Approach." (1987) pp. 37-72.
Hjelmeland, L. M. "Solubilization of Native Membrane Proteins," Method in Enzymology, vol. 182 (1990), pp. 253-263.
Hjelmeland, L. M. "Removal of Detergents from Membrane Proteins.", Methods in Enzymology, vol. 182 (1990) pp. 277-282.
Aebersold, et al., "Internal Amino Acid Sequence Analysis of Proteins Separated by One or Two-Dimensional Gel Electrophoresis After in situ Protease Digestion on Nitrocellulose.", Proceedings of the National academy of Sciences, USA, vol. 84, (1987) pp. 6970-6974.
Goldberg, et al., "Abundance, Diversity and Regulation of mRNA Sequence Sets in Soybean Embryogenesis.", Developmental Biology, vol. 83 (1981) pp. 201-217.
Jaye, et al., "Isolation of Human Anti-Haemophilic Factor IX cDNA Clone Using a Unique 52-Base Acid Sequence of Bovine Factor IX.", Nucleic Acids Research, vol. 11, No. 8 (1983) pp. 2325-2335.
Radke, et al., "Transformation of Brassica Napus L. Using Agrobacterium Tumefaciens: Developmentally Regulated Expression of a Reintroduced Napin Gene"., Theoretical and Applied Genetics, vol. 75 (1988) pp. 685-694.
Yermanos, D. M., "Quantitative and Qualitative Characteristics of Jojoba Seed.", The Journal of the American Oil Chemistry Society, vol. 53 (1976) pp. 685-694.
Ohlrogge, et al., "Studies on Biosynthesis of Waxes by Developing Jojoba Seed Tissue.", Lipids, vol. 13, No. 3 (1978) pp. 202-210.
Wildner, et al., "Wax Esther Biosynthesis in Euglena gracilis.", Abstract from Southwest Consortium on plant Genetics and Water Resources, Las Cruces, N.M., 5th Annual Meeting.
Inui, et al., "Fatty Acid Synthesis in Mitochondria of Euglena gracilis.", European Journal of Biochemistry, vol. 142 (1984) pp. 121-126.
Metz James G.
Pollard Michael R.
Calgene Inc.
Fox David T.
Rories Charles
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