Fatty acid synthetase, polynucleotide encoding the same, and...

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound

Reexamination Certificate

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C435S252300, C435S252330, C435S254100, C435S320100, C435S183000, C536S023200

Reexamination Certificate

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07927845

ABSTRACT:
The present invention provides fatty acid synthetases which are responsible for novel fatty acid synthesis, polynucleotides which encode such fatty acid synthetases (e.g., a polynucleotide comprising (a) a polynucleotide consisting of the nucleotide sequence of Positions 1 to 12486 of SEQ ID NO: 1, or (b) a polynucleotide which hybridizes under stringent conditions to a polynucleotide comprising a nucleotide sequence complementary to the nucleotide sequence of Positions 1 to 12486 of SEQ ID NO: 1, and which encodes a protein having a fatty acid synthetase activity), expression vectors and transformants comprising such polynucleotides, methods for producing food and other products using such transformants, food products produced by such methods, and methods for assessing and selecting lipid-producing test fungi.

REFERENCES:
patent: 2004/0172681 (2004-09-01), Voelker et al.
patent: 2005/0191679 (2005-09-01), Metz et al.
patent: 2008/0138874 (2008-06-01), Ochiai et al.
patent: 8-205900 (1996-08-01), None
patent: 2001-245687 (2001-09-01), None
patent: 2005-287403 (2005-10-01), None
patent: 01/40514 (2001-06-01), None
“Schizosaccharomyces pombe fatty acid synthase subunit alpha” XP-002450605, retrieved from EBI, Database Acc. No. ADQ26426 (2004).
Takeno et al. “Transformation of Oil-Producing Fungus,Mortierella alpina1S-4, Using Zeocin, and Application to Arachidonic Acid Production”J. Biosci. Bioengineer. 100(6):617-22 (2005).
Schweizer et al. “Microbial Type I Fatty Acid Synthases (FAS): Major Players in a Network of Cellular FAS Systems”Microbiol. Mol. Biol. Rev. 68(3):501-517 (2004).
Karlin et al. “Methods for assessing the statistical significance of molecular sequence features by using general scoring schemes”Proc. Natl. Acad. Sci. USA87:2264-2268 (1990).
Karlin et al. “Applications and statistics for multiple high-scoring segments in molecular sequences”Proc. Natl. Acad. Sci. USA90:5873-5877 (1993).
Zoller et al. “Oligonucleotide-directed mutagenesis using M13-derived vectors: an efficient and general procedure for the production of point mutations in any fragment of DNA”Nuc. Acids Res. 10(20):6487-6500 (1982).
Dalbadie-McFarland et al. “Oligonucleotide-directed mutagenesis as a general and powerful method for studies of protein function”Proc. Natl. Acad. Sci. USA79:6409-6413 (1982).
Carter et al. “Improved oligonucleotide site-directed mutagenesis using M13 vectors”Nuc. Acids Res. 13(12):4431-4443 (1985).
Kunkel, T.A. “Rapid and efficient site-specific mutagenesis without phenotypic selection”Proc. Natl. Acad. Sci. USA82:488-492 (1985).
Stoops et al. “Studies on the Yeast Fatty Acid Synthetase”J. Biol. Chem. 253(12):4464-4475 (1978).
Struhl et al. “High-frequency transformation of yeast: Autonomous replication of hybrid DNA molecules”Proc. Natl. Acad. Sci. USA76(3):1035-1039 (1979).
Karin et al. “Primary structure and transcription of an amplified genetic locus: TheCUP1locus of yeast”Proc. Natl. Acad. Sci. USA81:337-341 (1984).
Mackenzie et al. “Isolation and Use of a Homologous Histone H4 Promoter and a Ribosomal DNA Region in a Transformation Vector for the Oil-Producing FungusMortierella alpine” Appl. Environ. Microbiol. 66(11):4655-4661 (2000).
Hinnen et al. “Transformation of yeast”Proc. Natl. Acad. Sci. USA75(4):1929-1933 (1978).
Ito et al. “Transformation of Intact Yeast Cells Treated with Alkali Cations”J. Bacteriol. 153(1):163-168 (1983).
English language Abstract of JP 2001-245687, (Sep. 11, 2001).
English language Abstract of JP 8-205900, (Aug. 13, 1996).
English language Abstract of JP 2005-287403, (Oct. 20, 2005).

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