Multicellular living organisms and unmodified parts thereof and – Plant – seedling – plant seed – or plant part – per se – Higher plant – seedling – plant seed – or plant part
Reexamination Certificate
2011-04-05
2011-04-05
McElwain, Elizabeth F (Department: 1638)
Multicellular living organisms and unmodified parts thereof and
Plant, seedling, plant seed, or plant part, per se
Higher plant, seedling, plant seed, or plant part
C800S281000, C536S023200, C435S410000, C426S615000
Reexamination Certificate
active
07919685
ABSTRACT:
The invention relates generally to methods and compositions concerning desaturase enzymes that modulate the number and location of double bonds in long chain poly-unsaturated fatty acids (LC-PUFA's). In particular, the invention relates to methods and compositions for improving omega-3 fatty acid profiles in plant products and parts using desaturase enzymes and nucleic acids encoding for such enzymes. In particular embodiments, the desaturase enzymes areTetraselmis suecicadelta 6 desaturases. Also provided are improved soybean oil compositions having GLA and SDA.
REFERENCES:
patent: 4910141 (1990-03-01), Wong et al.
patent: 5057419 (1991-10-01), Martin et al.
patent: 5097093 (1992-03-01), Vanderventer et al.
patent: 5349123 (1994-09-01), Shewmaker et al.
patent: 5376541 (1994-12-01), Kawashima et al.
patent: 5405765 (1995-04-01), Vasil et al.
patent: 5443974 (1995-08-01), Hitz et al.
patent: 5484956 (1996-01-01), Lundquist
patent: 5498830 (1996-03-01), Barry et al.
patent: 5552306 (1996-09-01), Thomas et al.
patent: 5591616 (1997-01-01), Hiei et al.
patent: 5614393 (1997-03-01), Thomas et al.
patent: 5614400 (1997-03-01), Cahoon et al.
patent: 5668292 (1997-09-01), Somerville et al.
patent: 5880275 (1999-03-01), Fischhoff et al.
patent: 5886244 (1999-03-01), Tomes et al.
patent: 5952544 (1999-09-01), Browse et al.
patent: 5968809 (1999-10-01), Knutzon et al.
patent: 5972664 (1999-10-01), Knutzon et al.
patent: 6051754 (2000-04-01), Knutzon
patent: 6075183 (2000-06-01), Knutzon
patent: 6117677 (2000-09-01), Thompson et al.
patent: 6136574 (2000-10-01), Knutzon et al.
patent: 6319698 (2001-11-01), Barclay
patent: 6355861 (2002-03-01), Thomas
patent: 6384301 (2002-05-01), Martinell et al.
patent: 6451567 (2002-09-01), Barclay
patent: 6459018 (2002-10-01), Knutzon
patent: 6603061 (2003-08-01), Armstrong et al.
patent: 6803499 (2004-10-01), Anderson et al.
patent: 7037692 (2006-05-01), Thompson et al.
patent: 7622632 (2009-11-01), Ursin et al.
patent: 7705215 (2010-04-01), Adams et al.
patent: 2005/0132441 (2005-06-01), Damude et al.
patent: 2005/0132442 (2005-06-01), Yadav et al.
patent: 2006/0156435 (2006-07-01), Ursin et al.
patent: 2008/0063691 (2008-03-01), Ursin et al.
patent: 2008/0260929 (2008-10-01), Ursin et al.
patent: 2010/0212045 (2010-08-01), Ursin et al.
patent: 0 537 178 (1994-08-01), None
patent: 0 550 162 (2001-03-01), None
patent: 0 644 263 (2002-12-01), None
patent: 0 561 569 (2003-06-01), None
patent: 0 616 644 (2003-07-01), None
patent: 0 736 598 (2004-08-01), None
patent: WO 91/13972 (1991-09-01), None
patent: WO 93/06712 (1993-04-01), None
patent: WO 93/11245 (1993-06-01), None
patent: WO 94/11516 (1994-05-01), None
patent: WO 94/18337 (1994-08-01), None
patent: WO 96/10086 (1996-04-01), None
patent: WO 96/21022 (1996-07-01), None
patent: WO 97/21340 (1997-06-01), None
patent: WO 97/30582 (1997-08-01), None
patent: WO 97/46219 (1997-12-01), None
patent: WO 97/46220 (1997-12-01), None
patent: WO 98/45460 (1998-10-01), None
patent: WO 98/46763 (1998-10-01), None
patent: WO 99/64614 (1999-12-01), None
patent: WO 02/081668 (2002-10-01), None
patent: WO 02/092073 (2002-11-01), None
patent: WO 03/075670 (2003-03-01), None
patent: WO 03/072784 (2003-09-01), None
patent: WO 03/099216 (2003-12-01), None
patent: WO 2005/021761 (2005-03-01), None
patent: WO 2005/118814 (2005-12-01), None
Broun et al, Science 282: 1315-1317, Nov. 13, 1998.
Van de Loo et al, PNAS, USA 92:6743-6747, Jul. 1995.
Doerks et al, TIG 14(6):248-250, Jun. 1998.
Brenner, S.E., TIG 15(4): 132-133, Apr. 1999.
Bork et al, TIG 12(10):425-427, Oct. 1996.
Traitler et al., “Fractionation of blackcurrant seed oil,”JAOCS, 65(5):755-760, 1988.
U.S. Appl. No. 08/113,561, filed Aug. 25, 1993, Adams.
“Exciting prospects for stearidonic acid seed oils,”Lipid Technology, Nov. 1996.
Alonso and Garcia-Maroto, “Plants as ‘chemical factories’ for the production of polyunsaturated fatty acids,”Biotechnology Advances, 18(6):481-497, 2000.
Arondel et al., “Map-based cloning of a gene controlling omega-3 fatty acid desaturation in arabidopsis,”Science, 258:1353-1355, 1992, Abstract only.
Casas et al., “Transgenic sorghum plants via microprojectile bombardment,”Proc. Natl. Acad. Sci. USA, 90:11212-11216, 1993.
Conti et al., “y-linolenic acid production by solid-state fermentation of mucorales strains on cereals,”Bioresource Technology, 76:283-286, 2001.
Covello et al., “Functional expression of the extraplastidial arabidopsis thaliana oleate desaturase gene (FAD2) inSaccharomyces cerevisiae,” Plant Physiology, 111:223-226, 1996.
EBI Accession No. AEE85555 dated Feb. 23, 2006.
EBI Accession No. AEE85556 dated Feb. 23, 2006.
Fox et al., “Stearoyl-acyl carrier protein delta9desaturase from ricinus communis is a diiron-oxo protein,”Proc. Natl. Acad. Sci., 90:2486-2490, 1993.
Garcia-Maroto et al, “Cloning and molecular characterization of the delta6-desaturase from two echium plant species: production of GLA by heterologous expression in yeast and tobacco,”Lipids, 37(4):417-26, 2002.
GenBank Accession No. AX577009 dated Jan. 8, 2003.
GenBank Accession No. AY234125, dated May 4, 2003.
GenPept Accession No. AAF08685 dated Nov. 18, 1999.
Horrobin, “Fatty acid metabolism in health and disease: the role of delta-6-desaturase1,”Am. J. Clin. Nutr., 57(Supp.):732S-737S, 1993.
James and Cleland, “Dietary n-3 fatty acids and therapy for reumatoid arthritis,”Semin Arthritis Rheum, 27(2):85-97, 1997.
Kossmann et al., In: Carbohydrate Bioengineering, “Transgenic plants as a tool to understand starch biosynthesis,” Petersen et al. (Eds.), Elsevier Science B.V.; Amsterdam, 1995.
Libisch et al., “Chimeras of Delta6-fatty acid and Delta8-sphingolipid desaturases,”Biochem Biophys Res Commun, 279(3):779-85, 2000.
McDonough et al., “Specificity of unsaturated fatty acid-regulated expression of theSaccharomyces cerevisiaeOLE1 gene,”J. of Biological Chemistry, 267(9):5931-5936, 1992.
Meesapyodsuk et al., “Characterization of the regiochemistry and cryptoregiochemistry of aCaenorhabditis elegansfatty acid desaturase (FAT-1) expressed inSaccharomyces cerevisiae,” Biochemistry, 39(39):11948-54, 2000.
Michaelson et al., “Functional identification of a fatty acid delta5 desaturase gene fromCaenorhabditis elegans,”FEBS Lett, 439(3):215-8, 1998.
Michaelson et al., “Isolation and characterization of a cDNA encoding a Delta8 sphingolipid desaturase fromAquilegia vulgaris,”Biochem Soc Trans, 30(Pt 6):1073-5, 2002.
Napier et al., “A new class of cytochrome b5 fusion proteins,”Biochem J, 328:717-720, 1997.
Napier et al., “Identification of aCaenorhabditis elegansDelta6-fatty-acid-desaturase by heterologous expression inSaccharomyces cerevisiae,” Biochem J, 330(Pt 2):611-4, 1998.
Napier et al., “The role of cytochrome b5 fusion desaturases in the synthesis of polyunsaturated fatty acids,”Prostaglandins Leukot Essent Fatty Acids, 68(2):135-43, 2003.
Post-Beittenmiller et al., “Expression of holo and Apo forms of spinach acyl carrier protein-I in leaves of transgenic tobacco plants,”The Plant Cell, 1:889-899, 1989.
Reddy et al., “Expression of a cyanobacterial delta6-desaturase gene results in y-linolenic acid production in transgenic plants,”Nature Biotechnology, 14:639-642, 1996.
Reddy et al., “Isolation of a delta 6-desaturase gene from the cyanobacteriumsynechocystissp. strain PCC 6803 by gain-of-function expressionanabaenasp. strain PCC 7120,”Plant Mol. Biol., 22(2):293-300, 1993, Abstract only.
Sayanova et al., “Histidine-41 of the cytochrome b5 domain of the borage delta6 fatty acid desaturase is essential for enzyme activity,”Plant Physiol, 121:641-646, 1999.
Sayanova et al., “Identification of primula fatty acid delta 6-desaturases with n-3 substrate preferences,”FEBS Letters, 542:100-104, 2003.
Froman Byron
Ursin Virginia
Valentin Henry E.
McElwain Elizabeth F
Monsanto Technology LLC
Olsen, Esq. Byron V.
SNR Denton US LLP
LandOfFree
Fatty acid desaturases from Tetraselmis suecica does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Fatty acid desaturases from Tetraselmis suecica, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Fatty acid desaturases from Tetraselmis suecica will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2739243