Fatty acid desaturases and mutant sequences thereof

Details Fatty acid desaturases and mutant sequences thereof Fatty acid desaturases and mutant sequences thereof

2005-11-22

2005-11-22

McElwain, Elizabeth F. (Department: 1638)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S023600

Reexamination Certificate

active

06967243

ABSTRACT:
Seeds, plants and oils are provided having high oleic acid; low linoleic acid; and low linoleic acid plus linolenic acid; and advantageous functional or nutritional properties. Plants are disclosed that contain a mutation in a delta-12 or delta-15 fatty acid desaturase gene. Preferred plants are rapeseed and sunflower plants. Plants carrying such mutant genes have altered fatty acid composition in seeds. In one embodiment, a plant contains a mutation in a region having the conserved motif His-Xaa-Xaa-Xaa-His, found in delta-12 and delta-15 fatty acid desaturases. A preferred motif has the sequence His-Glu-Cys-Gly-His. A preferred mutation in this motif has the amino acid sequence His-Lys-Cys-Gly-His. Nucleic acid fragments are disclosed that comprise a mutant delta-12 or delta-15 fatty acid desaturase gene sequence.

REFERENCES:
patent: 4627192 (1986-12-01), Fick
patent: 4948811 (1990-08-01), Spinner et al.
patent: 5387758 (1995-02-01), Wong et al.
patent: 5434283 (1995-07-01), Wong et al.
patent: 5545821 (1996-08-01), Wong et al.
patent: 5625130 (1997-04-01), Grant et al.
patent: 6372965 (2002-04-01), Lightner et al.
patent: 323 753 (1989-07-01), None
patent: WO 91/15578 (1991-10-01), None
patent: WO 92/03919 (1992-03-01), None
patent: WO 93/11245 (1993-06-01), None
patent: WO 94/11516 (1994-05-01), None
BRL Catalog and Reference Guide, Sequencing Primers, p. 61, 1989.
Arondel et al., Science, 1992, 258:1153-1155.
Brunklaus-Jung et al., 1987, Plant Breeding, 98:9-16.
Canvin, Can. J. Botany, 1965, 43:63-69.
Circulation, vol. XLI, Suppl. I, Keys. Ed., pp. 1162-1183 (1970).
Conner et al., Coronary Heart Disease: Prevention, Complications, and Treatment, 1985, pp. 43-64.
Classen, Oral Presentation, GCIRC 8th International Rapeseed Congress, Saskatoon, Saskatchewan, Jul. 9-11, 1991, pp. 390-395.
Craig, Can. J. Plant Science, 1961, 41:204-210.
Downey et al., Can. J. Plant Sci., 1963, 43:271-275.
Evans et al., JAOCS, 1970, 48:711-714.
Fox et al., Proc. Natl. Acad. Sci. USA, 1993, 90:2486-2490.
Gaillard, The Biochemistry of Plants, Stumpf, Ed. Academic Press, NY, 1980, 4:85-116.
Garg et al., New England J. Med., 1988. 319:829-834.
Gaul, Radiation Botany, 1964, 4:155-232.
Grundy, New England J. Med., 1986, 314:745-748.
Hawrysh, Chemistry, Analysis, and Nutritional Effects, “Stability of Canola Oil,” Shahidi, Ed., Van Nostrand Reinhold, NY, 1990, Chap. 7, pp. 99-122.
Hitz et al., Plant Physiol., 1994, 103:635-641.
Hoffman et al., Theor. Appl. Genet., 1982, 61:225-232.
Kirk-Othmer Encyclopedia of Chemical Technol.. 3rd Edition, 1980, 9:795-831.
Kondra et al., Can. J. Plant Sci., 1976, Selection for Oleic, Linoleic and Linolenic Acid Content in F2 Populations of Rape, 56:961-966.
Kosteoglu et al., Chemistry, Analysis, and Nutritional Effects, Hydrogenation of Canola Oil, Van Nostrand Reinhold, NY, 1990, Chap. 8, pp. 123-148.
Lindqvist et al., The EMBO Journal, 1996, 15(16):4081-4092.
Mattson, J. Am. Diet. Assoc., 1989, 89:387-390.
Mensink et al., New England J. Med., 1989, 321:436-441.
Mensink et al., New England J. Med., 1990, 323(7):439-445.
Neidleman, Temperature Effects in the Biosyntheses of Unique Fats and Fatty Acids, Proc. of the World Conf. on Biotech. Fats. Oils Ind.. 1988.
Okuley et al., Plant Cell, 1994, 6:147-158.
Paul et al., Theor. Appl. Genet., 1986, 72:706-709.
Pleines and Friedt, Fat Sci. Technol., 1988. 90(5), 167-171.
Pleines et al., Abstract of 43rd Lecture Meeting of Deutsche Gesellschaft fur Feltwissenschaft in Hamburg, Sep. 30-Oct. 1, 1987.
Pleines et al., Abstract of Proceedings of the 7th International Rapeseed Congress, Pozman, Poland, May 11-14, 1987.
Rakow et al., J. Amer. Oil Chem. Soc., 1973, 50:400-403.
Rakow, Pflanzenzuchtg, 1973, 69:62-82.
Ram et al., Proceedings World Conference on Biotechnology for the Fats and Oils Industry, Sep. 27-Oct. 2, 1987.
Rennie et al., JAOCS, 1989, 66(1):1622-1624.
Robbelen et al., Pflanzenauchtg, 1975, 75:93-105.
Robbelen et al., Proceedings of the International Conference on the Scientific, Technology, and Marketing of Rapeseed and Rapeseed Products, Sep. 20-23, 1970.
Robbelen, In: Biotechnology for the Oils and Fats Industry, American Oil Chemists Society, 1984, pp. 97-105.
Roy et al., Pfanzenzuchtg, 1985, 95(3), 201-209.
Roy et al., Plant Breedings, 1987, 98:89-96.
Scarth et al., Can J. Plant Sci., 1988, 68:509-511.
Shanklin et al., Biochemistry, 1994, 33:12787-12794.
Shpora, Rape and Mustard Breeding for Oil Quality. Proceedings of the 7th International Rapeseed Congress, vol. 2, May 11-14, 1987, pp. 560-565.
Stefannson, High and Low Erucic Acid Rapeseed Oils, 1983, ed. N.T. Kenthies, Academic Press Inc., Canada, pp. 145-159.
Stefannson et al., Can. J. Plant Science, 1975, 55:343-344.
Töpfer et al., Science, 1995, 268:681-686.
Tremolieres et al., Phytochemistry, 1982, 2(1):41-45.
Ullrich et al., JAOCS, 1988. 65(8):1313-1317.
Western Canada Canola Rapeseed Recommendations Committee 1990 Cooperative Trial Date.
Williams et al., J. Am. Med. Assoc., 1987, 257:3251-3256.
Yadav et al., Plant Physiol., 1993, 103:467-476.

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