Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai
Patent
1986-05-16
1989-07-18
Robinson, Douglas W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ester doai
A61K 31215
Patent
active
048494518
ABSTRACT:
A fat emulsion containing a prostaglandin E.sub.1 alkyl ester represented by the general formula ##STR1## wherein R denotes an alkyl group having 1 to 30 carbon atoms. The fat emulsion can be administered intravenously, has a long half-life of its effective ingredient, prostaglandin E.sub.1 alkyl ester, in the living body as well as a focus selectivity.
REFERENCES:
patent: 3927213 (1975-12-01), Lippmann
patent: 4153727 (1979-05-01), Matsui et al.
patent: 4340594 (1982-07-01), Mizushima et al.
patent: 4443473 (1984-04-01), Buckwalter
Remington's Pharmaceutical Sciences, 16th ed., Mack Publishing Company, pp. 1453-1457 (1980).
The Merck Index, 10th Ed., Windholz, Eds., published by Merck & Co., Inc. Rahway, N.J., 1983, 2181, "Cholesterol", p. 312.
Aihara Hironaka
Mizushima Yutaka
Okamoto Hiroyuki
Otomo Susumu
Suyama Tadakazu
Kilcoyne J.
Robinson Douglas W.
Taisho Pharmaceutical Co. Ltd.
The Green Cross Corporation
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