Farnesyl transferase inhibitors

Details Farnesyl transferase inhibitors Farnesyl transferase inhibitors

2006-09-05

2006-09-05

Solola, Taofiq (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S343000, C514S378000, C514S424000, C548S240000, C548S541000, C546S208000, C546S278400

Reexamination Certificate

active

07101897

ABSTRACT:
This invention relates to compounds of formula (I) that inhibit farnesylation of gene products through inhibition of the enzyme farnesyl-protein transferase (FPTase). The invention also relates to methods of manufacturing the compounds, pharmaceutical compositions and methods of treating diseases, especially cancer, which are mediated through farnesylation.

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