Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-10-31
2006-10-31
Seaman, D. Margaret (Department: 1625)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C546S156000, C544S284000, C514S311000, C514S314000, C514S315000
Reexamination Certificate
active
07129356
ABSTRACT:
This invention comprises the novel compounds of formula (I)wherein r, s, t, Y1, Y2, Z, R1, R2, R3, R4, R5, R6and R7have defined meanings, having farnesyl transferase inhibiting activity; their preparation, compositions containing them and their use as a medicine.
REFERENCES:
patent: 5612354 (1997-03-01), Sanz et al.
patent: 0371564 (1995-07-01), None
patent: WO 97/16443 (1997-05-01), None
patent: WO 97/16443 (1997-05-01), None
patent: WO 97/21701 (1997-06-01), None
patent: WO 97/21701 (1997-06-01), None
patent: WO 98/40383 (1998-09-01), None
patent: WO 98/49157 (1998-11-01), None
patent: WO 98/49157 (1998-11-01), None
patent: WO 98/55124 (1998-12-01), None
patent: WO 00/01386 (2000-01-01), None
patent: WO 00/01411 (2000-01-01), None
patent: WO 00/12498 (2000-03-01), None
patent: WO 00/12498 (2000-03-01), None
patent: WO 00/12499 (2000-03-01), None
patent: WO 00/12499 (2000-03-01), None
patent: WO 00/39082 (2000-07-01), None
patent: WO 00/47574 (2000-08-01), None
patent: WO 01/53289 (2001-07-01), None
Kohl et al., “Selective Inhibition of ras-Dependent Transformation by a Famesyltransferase Inhibitor.”Science, 1993, pp. 1934-1937, vol. 260, No. 5116.
Rak et al., “Mutant ras Oncogenes Upregulate VEGF/VPF Expression: Implications for Induction and Inhibition of Tumor Angiogenesis.”Cancer Research, 1995, pp. 4575-4580, vol. 55, No. 20.
Angibaud Patrick Rene
Venet Marc Gaston
Janssen Pharmaceutica N.V.
Seaman D. Margaret
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