Farnesyl protein transferase inhibitors as antitumor agents

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S290000, C544S361000, C546S093000

Reexamination Certificate

active

07342016

ABSTRACT:
Disclosed are novel tricyclic compounds represented by the formula (1.0):and a pharmaceutically acceptable salt or solvate thereof. The compounds are useful for inhibiting farnesyl protein transferase. Also disclosed are pharmaceutical compositions comprising compounds of formula 1.0. Also disclosed are methods of treating cancer using the compounds of formula 1.0.

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