Farnesyl-protein transferase inhibitors

Details Farnesyl-protein transferase inhibitors Farnesyl-protein transferase inhibitors

1998-02-25

2000-04-18

Richter, Johann

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

514139, 514468, 514470, 549299, 549305, 549313, 562408, A61K 3134, A61K 3166, C07D30793, C07C 53136

Patent

active

060515651

ABSTRACT:
Substantially pure preparations of phosphosesquiterpenes are described. The compounds inhibit farnesyl-protein transferase activity and are useful for the treatment of cancer. Methods for inhibiting farnesyl-protein transferase activity are also described.

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