Farnesyl derivatives and pharmaceutical compositions containing

Details Farnesyl derivatives and pharmaceutical compositions containing Farnesyl derivatives and pharmaceutical compositions containing

1994-11-10

1998-01-06

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514567, 514568, 514576, 514602, 514603, 514618, 514619, 514622, 558413, 558418, 558423, 562 45, 562 47, 562432, 562458, 562473, 564 85, 564 86, 564 87, 564162, 564163, 564165, 564166, 564176, A61K 31275, C07C 6306, C07C25549, C07C23364

Patent

active

057055289

ABSTRACT:
Novel farnesyl derivatives which are inhibitors of the prenylated protein thyltransferase enzyme, and useful as anti-cancer drugs, have the following formula: ##STR1## wherein R.sup.1 represents farnesyl, geranyl or geranyl-geranyl;

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