Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1988-05-23
1991-06-04
Gerstl, Robert
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C07D27748
Patent
active
050215825
ABSTRACT:
It is described the preparation of the famotidine polymorphs with low melting point and relative high or low apparent densities. They differ from the polymorph of high melting point and high density, in the physical-chemical and biological properties, of interest in galenic formulations and preparation of the drug.
REFERENCES:
patent: 4496737 (1985-01-01), Hoffman
patent: 4894459 (1990-01-01), Bod
O.G. U.S. P.T.O. 1-16-90, p. 1411.
Haleblian, J. Pharm. Science, 58, 911, (1969).
Ballester-Rodes Montserrat
Palomo-Coli Antonio L.
Palomo-Nicolau Francisco E.
Centro Marga Para La Investigacion S.A.
Gerstl Robert
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