Family of anti-carcinoembryonic antigen chimeric antibodies

Details Family of anti-carcinoembryonic antigen chimeric antibodies Family of anti-carcinoembryonic antigen chimeric antibodies

1995-06-06

1998-09-15

Feisee, Lila

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424 111, 4241331, 4241921, 424934, 435 723, 435 7021, 435 697, 435 696, 4351723, 4353201, 514 44, 5303873, 5303877, A61K 39395, C07K 1630, C07H 2104, C12N 1513

Patent

active

058080333

ABSTRACT:
The present invention discloses novel chimeric monoclonal antibodies directed against human carcinoembryonic antigen, having antigen-specific variable regions. DNA constructs for the light and heavy chain variable regions comprising the novel antibodies of the invention are also disclosed. Eukaryotic host cells capable of expression of the chimeric antibodies and comprising the novel chimeric antibody-encoding DNA constructs are also described.

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