FADD-like anti-apoptotic molecules, methods of using the same, a

Details FADD-like anti-apoptotic molecules, methods of using the same, a FADD-like anti-apoptotic molecules, methods of using the same, a

1997-05-20

2000-03-14

Huff, Sheela

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

435 691, 4353201, 435 723, 530324, 514 44, C07H 2100, C12P 2106, C12N 1500, G01N 33574

Patent

active

060374616

ABSTRACT:
Two FADD-like anti-apoptotic proteins that regulate Fas/TNFR1- or UV-induced apoptosis are disclosed. Nucleotide sequences encoding the proteins are disclosed as are methods of using the nucleic acid molecules and making the proteins. Pharmaceutical compositions and methods of using the same are disclosed. Reagents, kits and methods of identifying compounds that inhibit anti-apoptotic activity of the proteins and methods of identifying compounds that inhibit binding activity of the proteins are disclosed.

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