Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2006-09-19
2006-09-19
Slobodyansky, Elizabeth (Department: 1652)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S018000, C435S195000
Reexamination Certificate
active
07108987
ABSTRACT:
The present invention provides a novel protein that regulates degranulation of mast cells (degranulation regulator), a gene encoding it, a protein (conjugate factor) that interacts with the regulator, a gene encoding it, a screening method of an inhibitor of the degranulation, which uses this degranulation regulator and the conjugate factor, an inhibitor obtained by the screening method and the like.
REFERENCES:
patent: 5843717 (1998-12-01), Hillman et al.
patent: 6391580 (2002-05-01), Hillman et al.
patent: WO 87/06127 (1987-10-01), None
patent: WO 99/42586 (1999-08-01), None
patent: WO 00/58464 (2000-10-01), None
patent: WO 01/64887 (2001-09-01), None
Wagner et al (1995) Biochemical and Biophysicam Res. Communications, vol. 207, pp. 950-956.
Oberhauser et al. (1994) FEBS Letters, vol. 339, pp. 171-174.
Masuda et al., “Rab37 is a novel mast cell specific GTPase localized to secretory granules;”FEBS Letters, 470 (1), 61-64 (Mar. 17, 2000).
Mizuki et al., “Functional modules and expression of mouse p40phoxand p67phox, SH3-domain-containing proteins involved in the phagocyte NDAPH oxidase complex,”European Journal of Biochemistry, 251 (3), 573-582 (1998).
Leto et al., “Cloning of a 67-kD Neutrophil Oxidase Factor with Similarity to a Noncatalytic Region of p60c-src,”Science, 248, 727-730 (1990).
Belik et al., “Correlation between structure and radioprotective activity (RPA) in thiazole derivatives,”Radiats. Biol. Radioecol., 33 (6), 824-830 (1993).
Jager et al., “Serological Cloning of a MelanocyterabGuanosine 5'-Triphosphate-binding Protein and a Chromosome Condensation Protein from a Melanoma Complementary DNA Library,”Cancer Research, 60 (13), 3584-3591 (2000).
Gonzalez et al.,Cell, 96(6): 755-758 (1999).
Roa et al.,Journal of Immunology, 159(6): 2815-2823 (1997).
Ido Motoharu
Yamada Tsuyoshi
Dainippon Pharmaceutical Co., Ltd.
Leydig Volt & Mayer, Ltd.
Slobodyansky Elizabeth
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