Factor Xa inhibitor and pharmaceutical compositions containing s

Drug – bio-affecting and body treating compositions – Extract – body fluid – or cellular material of undetermined... – Body fluid or exudate or transudate other than snake venom,...

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424550, 530855, 514 21, A61K 3562

Patent

active

054035961

ABSTRACT:
A novel anticoagulant/modulator factor isolated from the saliva of the meinal leech Hirudo medicinalis, specifically inhibiting bovine Xa factor but not inhibiting bovine thrombin.

REFERENCES:
patent: 4588587 (1986-05-01), Gasic
patent: 4791100 (1988-12-01), Kramer
patent: 4832849 (1989-05-01), Cardin
Gasic, G. J., Viner, E. D., et al. Cancer Research (1983) 43: 1633-1636.
Gasic, G. J., Iwakawa, A., et al., Cancer Res. (1984) 44: 5670-5676.
Gasic, G. J., Gasic, T. B., et al., Chemical Abstracts (1986) 110: 185955w.
Baskova, I. P., et al., Chemical Abstracts (Mar. 2, 1987) 106: 60996w.
Condra, C., et al., Thrombosis and Haemostasis (1989) 61(3): 437-441.

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