Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 25 or more amino acid residues in defined sequence
Patent
1994-03-04
1998-08-18
Jacobson, Dian C.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
25 or more amino acid residues in defined sequence
530300, 514 12, C07K 1481, A61K 3816, A61K 3857
Patent
active
057959544
ABSTRACT:
A potent serine protease inhibitor capable of inhibiting Factor VIIa, Factor XIa, plasma kallikrein, and plasmin is provided. The inhibitor is provided in a pharmaceutical composition for treatment of diseases where inhibition of Factor VIIa, Factor XIa, plasma kallikrein, or plasmin is indicated.
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Van Den Besselaar
Dennis Mark S.
Lazarus Robert A.
Genentech Inc.
Jacobson Dian C.
Kubinec Jeffrey S.
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