Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1997-06-23
1999-01-12
Richter, Johann
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514507, 514508, 514740, 544354, 562622, 564123, 564229, A61K 31495, C07C25100, C07C25134, C07D24136
Patent
active
058590102
ABSTRACT:
The invention relates to novel compounds that potentiate zinc ion inhibition of the activity of factor VIIa or tissue factor--factor VIIa complex having the formula Ia and Ib and pharmaceutical salts thereof as well as pharmaceutical compositions comprising said novel compounds. The invention is further related to the use of said compositions for inhibiting clotting activity, tissue factor activity and factor VIIa activity.
REFERENCES:
patent: 5514680 (1996-05-01), Weber et al.
patent: 5639739 (1997-06-01), Dominguez et al.
patent: 5693515 (1997-12-01), Clark et al.
Koshti et al., Tetrahedron Letters, vol., 35 No. 29, pp. 5157-5160 (1994).
Farkas et al., Chemical Abstracts, vol. 118, No. 8, p. 532 (Feb. 22, 1993).
Jakobsen Palle
Olsen Ole Hvilsted
Petersen Lars Christian
Richter Stefan Lutz
Gregg, Esq. Valeta
Novo Nordisk A S
Oswecki Jane C.
Richter Johann
Zelson Esq. Steve T.
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