Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Reexamination Certificate
2005-02-22
2005-02-22
Azpuru, Carlos A. (Department: 1615)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
C514S772300
Reexamination Certificate
active
06858222
ABSTRACT:
The invention provides tissue engineering compositions and methods wherein three-dimensional matrices for growing cells are prepared for in vitro and in vivo use. The matrices comprise biodegradable polymer fibers capable of the controlled delivery of therapeutic agents. The spatial and temporal distribution of released therapeutic agents is controlled by use of defined nonhomogeneous patterns of therapeutic agents in the matrices.
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Alikacem Nadir
Hu Zhibing
Nelson Kevin D
Radulescu Delia
Romero-Sanchez Andres A.
Azpuru Carlos A.
Board of Regents , The University of Texas System
Jenkens & Gilchrist P.C.
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