Fabrication of a cartilage implant

Details Fabrication of a cartilage implant Fabrication of a cartilage implant

2005-02-08

2005-02-08

Naff, David M. (Department: 1651)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

C424S093700, C424S423000, C435S177000, C435S395000

Reexamination Certificate

active

06852331

ABSTRACT:
A method of fabricating a cartilage implant including embedding and growing chondrocytes or mesenchymal stem cells in a three-dimensional substrate. The substrate contains randomly rewound α-helical monomers of type I collagen.

REFERENCES:
patent: 4609551 (1986-09-01), Caplan et al.
patent: 4642120 (1987-02-01), Nevo et al.
patent: 5876444 (1999-03-01), Lai
patent: 6530956 (2003-03-01), Mansmann
patent: 6623963 (2003-09-01), Muller et al.
Folch, et al.Stacks of Microfabricated Structures as Scaffolds for Cell Culture and Tissue Engineering. Biomedical Microdevices 2(3):207-214 (2000).
Freed, et al.Chondrogenesis in a Cell-Polymer-Bioreactor System. Experimental Cell Research 240:58-65 (1998).
Freed, et al.Joint resurfacing using allograft chondrocytes and synthetic biodegradable polymer scaffolds. Journal of Biomedical Materials Research 28:891-899 (1994).
Gillogly, et al.Treatment of Articular Cartilage Defects of the Knee With Autologous Chondrocyte Implantation. JOSPT 28(4):241-251 (Oct. 1998).
Minas, et al.Current Concepts in the Treatment of Articular Cartilage Defects. Orthopedics 20(6):525-538 (Jun. 1997).
Peterson, et al.Two- to 9-Year Outcome After Autologous Chondrocyte Transplantation of the Knee. Clinical Orthopedics and Related Research 374:212-234 (2000).
Yasui, et al.Primary Culture of Chondrocytes Embedded in Collagen Gels. Expl. Cell Biol. 50:92-100 (1982).

Affiliated with

Also associated with

Rating

Fabrication of a cartilage implant does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Fabrication of a cartilage implant, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Fabrication of a cartilage implant will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3502625