Fabrication method of multisensors chips for detecting analytes

Semiconductor device manufacturing: process – Having biomaterial component or integrated with living organism

Reexamination Certificate

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C257SE21158, 99

Reexamination Certificate

active

07138281

ABSTRACT:
A method includes (a) putting a multielectrodic chip lithographed in a wafer that contains between 2 and 2000 individually polarisable electrodes, in contact with a solution or suspension that includes modified colloidal particles with a (bio)chemical recognition element; (b) applying to an electrode of the multielectrodic chip, a potential between −1 and +2V vs. Ag/AgCl saturated, for a period of time between 1 and 300 seconds; (c) washing the chip after this stage (b); and (d) repeat the steps (b) and (c) as many times as needed to deposit a (bio)chemical recognition element, same or different to the one or ones previously deposited, on each one of the electrodes of that chip. The method is applicable for the fabrication of multisensors, particularly in chips and arrays for analytical and diagnostic applications.

REFERENCES:
patent: 2002/0171079 (2002-11-01), Braun et al.
patent: 2003/0203394 (2003-10-01), Eichen et al.

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