F.sub.0 ATP synthase subunit

Details F.sub.0 ATP synthase subunit F.sub.0 ATP synthase subunit

1997-03-11

1998-07-28

Patterson, Jr., Charles L.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435232, 4352523, 4353201, 536 232, C12N 1560, C12N 988

Patent

active

057861501

ABSTRACT:
The present invention provides a human ATP synthase subunit (ASYS) and polynucleotides which encode ASYS. The invention also provides expression vectors, host cells, agonists, antisense molecules, antibodies, or antagonists. The invention also provides methods for producing ASYS and for treating disorders associated with expression of ASYS.

REFERENCES:
Walker, JE and Collinson, IR, "The role of the stalk in the coupling mechanism of F.sub.1 F.sub.0 -ATPases" FEBS Letters 346: 39-43 (1994).
Collinson, I.R., et.al. (1994) Bichemistry 33, 7971-7978.
Walker, J. E., et. al. (1987) J. Mol. Biol. 197. 98-100.
Lippo, G., et. al. (1988) J. Biol. Chem. 263(35), 18627-18634.
Medd, S. M., et. al. (1993) Biochem. J. 293, 65-73.

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