Extraocular method of treating the eye with liquid perfluorocarb

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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424353, A61K 31025, A61K 3103

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active

044528183

ABSTRACT:
Extraocular ophthalmic preparations useful as therapeutic, lubricating or protective agents are disclosed. Liquid perfluorocarbons and substituted derivatives are the active components of the ophthalmic preparations. The neat perfluorocarbon liquids are not aqueous, wherefore, isotonicity and pH need not be considered in their preparation. Liquid sterility may be maintained without the addition of preservatives. Cornea and conjunctiva surfaces are provided with greater amounts of oxygen when the perfluorocarbon liquids are employed as eye drops.

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Product Information on Healon-Pharmacia Inc., 1980.
Retina, (1981), 1 (3), 227-231.
Wellcome Trends in Ophthal., 4 (1) (1982).
Agnew Chem. Int. Ed. Engl. 17, pp. 621-634 (1978).
Label for Fluosol-DA-20%-frozen.

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