Liquid purification or separation – Processes – Liquid/liquid solvent or colloidal extraction or diffusing...
Patent
1987-12-30
1990-03-20
Jones, W. Gary
Liquid purification or separation
Processes
Liquid/liquid solvent or colloidal extraction or diffusing...
210782, 210804, 424101, 494 37, B01D 1104
Patent
active
049099400
ABSTRACT:
A method of removing lipid soluble chemicals from a biological material containing the lipid soluble chemicals comprising bringing the biological material containing the lipid soluble chemicals into contact with an effective amount of an organic alcohol whose solubility in an aqueous solution at the temperature of use is .ltoreq.0.6% and/or a halogenated hydrocarbon having more than one type of halogen, agitating the resultant mixture and achieving a phase separation of the biological material and the organic alcohol and/or halogenated hydrocarbon. The method is particularly useful for producing relatively virus free physiologically acceptable plasma.
REFERENCES:
patent: 3958939 (1976-05-01), Jones
patent: 4481189 (1984-11-01), Prince
patent: 4540573 (1985-09-01), Neuvath et al.
patent: 4721730 (1988-01-01), Furuyoshi et al.
E. Tabor, D. L. Aronson, R. J. Gerety, "Removal of Hepatitis B Virus Infectivity from Factor OX Complex by Hepatitis B Immune Globulin", Lancet, (1980), 2, 68-70.
H. G. J. Brummelhuis, J. Over, L. A. Duivis-Vorst et al, "Contributions to the Optimal Use of Human Blood, IX Elimination of Hepatitis B Transmission by (Potentially) Infectious Plasma Derivatives", Vox San, (1983) 45, 205-216.
J. W. Oliphant, A. Hollaender, "Homologous Serum Janudice Experimental Inactivation of Etiologic Agent in Serum by Ultraviolet Irradiation", Public Health Rep., (1945), 61, 598-602.
S. S. Gellis, J. R. Neefe, J. Stokes Jr. et al., "Chemical, Clinical and Immunological Studies on the Products of Human Plasma Fractionation, XXXVI Inactivation of the Virus of Homologous Serum Hepatitis in Solutions of Normal Human Serum Albumin by Menas of Heat", J. Clin. Invest., (1984), 27, 239-244.
R. Murray, W. C. L. Diefenbach, "Effect of Heat on the Agent of Homologous Serum Hepatitis", Proc. Soc. Exp. Biol. Med., (1953), 84, 230-231.
J. P. Soulier, C. Blatix, A. M. Courouce et al, "Prevention of Virus B Hepatitis (SH) Hepatitis)", Am. J. Dis. Chid., (1972), 123, 429-434.
T. Shikata, T. Karasawa, K. Abe et al, "Incomplete Inactivation of Hepatitis B Virus After Heat-Treatment at 60.degree. C. for 10 hours", J. Infect. Dis., (1978), 138, 242-244.
E. Tabor, R. J. Gerety, "The Chimpanzee Animal Model for non-A non-B Hepatitis: New Applications", W. Szmuness, H. J. Alter, J. E. Maynard eds. Viral Hepatitis: 1981 International Symposium., Philadelphia: The Franklin Institute Press, (1981), 305-317.
Von N. Heimburger, H. Schwinn, P. Gratz et al, "Faktor VIII-Konzentrate, Hochgereinigt und in Losung Erhitzt, Arzneim-Thromb/Drug Res., (1981), 31, 619.
F. O. MacCallum, "Homologous Serum Hepatitis", Proc. Roy. Soc. Med., (1946), 39, 655.
R. Murray, J. W. Oliphant, J. T. Tripp et al, "Effect of Ultraviolet Radiation on Infectivity of Icterogenic Plasma, JAMA, (1955), 157, 8-14.
F. W. Hartman, G. A. LoGrippo, "Combined beta-Propiolactone and Ultraviolet Irradiation for Plasma Sterilization", F. W. Hartman, G. A. LoGrippo, J. G. Mateer et al, eds. Hepatitis Frontiers, Henry Ford Hosp. International Symposium, Boston, Little, Brown & Co., (1957), 407-416.
R. Kotitschke, W. Stephan, "Kominierte Behandlung von Gerinnungsfaktoren in Humanplasma mit .beta.-Bropiolacton and UV, Struktur und Funktion des Fibrinogens", H. Schroeer, G. Hauck, F. Zimmerman et al, eds., Blutgerinnung und Mikrozirkulation Stuttgart: Verlag, (1986), 222-228.
G. A. LoGrippo, H. Hayashi, "Efficacy of beta-Propiolactone with Ultraviolet Irradiation of Hepatitis B Antigen in Human Plasma Pools, Henry Ford Hosp. Med. J., (1973), 21, 181-186.
D. Heinrich, H. Berthold, "Application of Cold Sterilized Prothrombin Complex Concentrates in Man: Clinical and Serological Studies", The 13th International Congress of the World Federation of Hemophilia, Tel Aviv, Jul. 8-13, 1979.
A. M. Prince, B. Horowitz and B. Brotman, "Sterilization of Hepatitis and HTLV-III Viruses By Exposure to Tri(n-Butyl)Phosphate and Sodium Cholate", The Lancet, 706-710, Mar. 29, 1986.
S. M. Feinstone, K. B. Mihalik, T. Kamimura et al, "Inactivation of Hepatitis B Virus and non-A, non-B Hepatitis By Chloroform", Infect. Immunol., (1983), 41, 816-821.
D. W. Bradley, J. E. Maynard, H. Popper et al, "Posttransfusion non-A, non-B Hepatitis: Physiochemical Properties of Two Distinct Agents", J. Infect. Dis., (1983), 148, 254-265.
F. B. Hollinger, G. Dolana, W. Thomas et al, "Reduction in Rish of Hepatitis Transmission by Heat-Treatment of a Human Factor VIII Concentrate", J. Infect. Dis., (1984) 150, 250-262.
A. M. Prince, B. Horowitz, B. Brotman et al, "Inactivation of Hepatitis B and Hutchinson Strain non-A, non-B Hepatitis Viruses by Exposure to Tween 80 and Ether", Vox Sang, (1984), 46, 36-43.
E. Tabor, G. Murano, P. Snoy et al, "Inactivation of Hepatitis B Virus by Heat in Antithrombin III Stabilized with Citrate", Thromb. Res., (1981), 22, 233-238.
D. Menache, D. L. Aronson, "Measures to Inactivate Viral Contaminants of Pooled Plasma Products, R. Y. Dodd, L. F. Baker eds, Infection Immunity and Blood Transfusion Proc. XVII Annual Scientific Symposium, May 9-11, 1984, N.Y., Alan R. Loss, (1985), 407-423.
C. Rouzioux, S. Chamaret, L. Montagnier, V. Carnelli, G. Rolland, P. M. Mannucci, "Absence of Antibodies to AIDS Virus in Haemophiliacs Treated with Heat-Treated Factor VIII Concentrate, Lancet, (1985), February, 271-272.
M. Colombo, V. Carnelli, C. Gazengel, P. M. Mannucci, G. F. Savidge, K. Schimpf, "Transmission of non-A, non-B Hepatitis by Heat-Treated Factor VIII Concentrate", Lancet, (1985), Jul. 1-4.
W. Stephan, A. M. Prince, "Efficacy of Combined Treatment of Factor IX Complex (PPSB) with B-Propiolactone (b-PL) and Ultraviolet (UV) Irradiation", Haemostasis, (1981), 10, 67.
A. M. Prince, W. Stephan, B. Brotman, "B-Propiolactone/Ultraviolet Irradiation: A Review of its Effectiveness for Inactivation of Viruses in Blood Derivatives", Rev. Infect. Dis., (1983), 5, 92-107.
W. Stephan, A. M. Prince and R. Kotitschke, "Factor VIII Concentrate from Cold Sterilized Human Plasma", Develop Biol. Stand, (1983), 54, 491.
The LANCET, Sep. 28, 1985, p. 721, "Wet Heating for Safer Factor VIII Concentrate".
Viral Hepatitis: Second International Max von Pettenkofer Symposium, Marcel Dekker, Inc. New York and Basel, "Reduction of Infectivity of Hepatitis B Virus (HBV) and a Non-A, Non-B Hepatitis Agent By Heat Treatment of Human Anthihemophilic Factor (AHF) Concentrates", pp. 245-246, F. B. Hollinger, et al.
The Lancet, Jul. 27, 1985, p. 213, "Non-A, Non-B Hepatitis and Heat-Treated Factor VIII Concentrates".
A. Helenius and K. Sinous, "Solubilization of Membranes by Detergents", Biochem. Biophys. ACTA, (1975), 415, 29-79.
N. Heimburger, H. Schwinn, R. Mauler, "Factor VIII Concentrate, Hepatitis-Safe: Progress in the Treatment of Hemophilia A", Die Gelben Hefte, (1980), 20, 165-174 (including English language translation thereof).
Y. K. Yip, R. H. L. Pang, J. O. Oppenheim, M. S. Nashbar, D. Henriksen, T. Zerebecky]-Eckhardt, J. Vilcek, "Stimulation of Human Gamma Interferon Production by Diterpene Esters", Infect. and Immun., (1981), 131-139.
B. D. Williamson, E. A. Carswell, B. Y. Rubin, J. S. Prendergast, H. J. Old, "Human Tumor Necrosis Factor Produced by Human B-cells Lines: Synergistic Cytoxic Interaction with Human Interferon", Proc. Natl. Acad. Sci., U.S.A., (1983), 80.
B. Y. Rubin, S. L. Anderson, S. A. Sullivan, B. D. Williamson, E. A. Carswell, L. J. Old, "Purification and Characterization of a Human Tumor Necrosis Factor from the LukII Cell Line", Proc. Natl. Acad. Sci., U.S.A., (1985), 82, 6637-6641.
G. Dolana, D. Tse, W. Thomas et al, "Hepatitis Risk Reduction in Hemophilia: A Heated Factor VIII Preparation", Blood, Abstract 768 (1982), Supp. 1, 210a.
Bonomo Richard J.
Horowitz Bernard
Jones W. Gary
New York Blood Center Inc.
LandOfFree
Extraction of process chemicals from labile biological mixtures does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Extraction of process chemicals from labile biological mixtures , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Extraction of process chemicals from labile biological mixtures will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-791051