Extract from the leaves of Ginkgo biloba

Details Extract from the leaves of Ginkgo biloba Extract from the leaves of Ginkgo biloba

1997-08-25

2000-07-11

Lankford, Jr., Leon B.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Conjugate or complex

514 27, A61K 3578, A61K 3170

Patent

active

06086883&

ABSTRACT:
Extracts of leaves of Ginkgo biloba contain at least 25% glycolipids by weight, preferably at least 1% cerebrosides including galactocerebroside. The extract has less than 50 ppm of ginkgolic acid. The extract is prepared by recovering a lipid fraction which is mixed with alcohol providing an alcoholic medium. The alcoholic medium is treated in a chromatographic column with a mixture of acetone and toluene to remove neutral lipids and ginkgolic acid, and subsequently the alcoholic solution in the column is further treated with a mixture of acetone and water to extract the glycolipids. The extracts have shown activity in cosmetic and skin care applications.

REFERENCES:
patent: 4886904 (1989-12-01), Tanaka et al.
patent: 5389370 (1995-02-01), O'Reilly et al.
patent: 5512286 (1996-04-01), Schwabe
O'Reilly Annual Proc. Phytochem. Soc. of Europe, 1993 pp. 253-270.
Database WPI Section Ch, Week 8810, Derwent Pub., Ltd., London GB, JP,A,63 021 061, Jan. 28, 1988.
Patent Abstracts of Japan, vol. 012, No. 139, Apr. 27, 1988 & JP,A,62 255 433, Nov. 7, 1987.

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