Extrachromosomal regulation of expression

Details Extrachromosomal regulation of expression Extrachromosomal regulation of expression

1981-02-24

1983-02-22

Tanenholtz, Alvin E.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Enzymatic production of a protein or polypeptide

435317, 435 70, 435172, 435849, 435253, C12P 2100, C12P 2102, C12N 1500, C12N 120, C12N 100, C12R 119

Patent

active

043749275

ABSTRACT:
Microbiological methods, compositions and transformants are used for production of organic products for controlling cellular properties. Extrachromosomal elements are used which are subject to external modulation for production of a control element. The change in the amount of production of the control element allows for enhanced expression of a gene producing a poly(amino acid) product. The change in production of the control element allowing for enhanced gene expression of the product is accompanied by amplification of the product producing gene.

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